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apalutamide will lessen the level or effect of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with medicines which can be CYP3A4 substrates can lead to reduced exposure to those prescription drugs.However, you may have a relapse